Prepare Ingredients: Chop the nopales, jalapeño peppers, serrano peppers, onion, garlic, and tomato.
Cook Sauce: In a pot of boiling water, add the chilies, onion, garlic, and tomato. Cook until soft.
Cook Nopales: In a separate pan, cook the nopales with a little onion and salt until tender.
Brown Chicken: In a hot casserole, brown the chicken thighs in oil until golden on both sides.
Combine Ingredients: Add the cooked nopales to the browned chicken and pour the sauce over the top.
Simmer: Let everything boil until the chicken is cooked through.
Serve: Remove from heat and let cool slightly before serving.